Here are some potential causes of unexplained itching all over the body at night:
- Dry skin – Dry, flaky skin can become very itchy, especially when you get warm in bed at night. Using gentle moisturizers and humidifying the air can help.
- Allergies – Allergic reactions to foods, medications, dust mites, pet dander, etc. can cause itching. Try to identify and avoid triggers. Antihistamines may provide relief.
- Kidney disease – Advanced kidney disease can lead to accumulation of waste products that irritate the skin. See a doctor for evaluation.
- Liver disease – Conditions like cholestasis and hepatitis may cause intense full body itching. Seek medical attention to check liver function.
- Blood disorders – Rare disorders like polycythemia vera and lymphoma may first appear as unexplained itching. Get a blood test to check cell counts.
- Nerve disorders – Pinched nerves, multiple sclerosis and other neurological issues can cause itching. See a neurologist if itching persists.
- Pregnancy – Hormonal changes and stretching skin can cause itching late in pregnancy. Moisturize and avoid hot showers.
- Medication side effects – Itching can be a side effect of certain medications like opioids, antibiotics, blood pressure drugs. Consult your doctor.
- Psychological causes – Stress and anxiety may worsen itching. Relaxation techniques before bed may help reduce itching.
The itching is often worse at night because there are fewer distractions. Carefully reviewing any new medications or symptoms with your doctor can help determine the cause. Keeping the skin well-moisturized and nails short may provide some relief as well.